Genome-wide reconstruction of the intrinsic apoptosis pathway in Haemonchus contortus
This molecular framework highlights conserved structural features and developmental regulation of apoptosis in a parasitic nematode and provides a basis for functional studies to evaluate apoptotic regulators as potential targets for anthelmintic development.
Authors
- Jiangning Song (ORCID: https://orcid.org/0000-0001-8031-9086)
- Erinna F. Lee (ORCID: https://orcid.org/0000-0003-1255-9808)
- Neil D. Young (ORCID: https://orcid.org/0000-0001-8756-229X)
- Yanxiang Shen
- Brad E. Sleebs (ORCID: https://orcid.org/0000-0001-9117-1048)
- W. Douglas Fairlie (ORCID: https://orcid.org/0000-0002-2498-1160)
- Robin B. Gasser
- Bill C. H. Chang
Institutions
- The University of Melbourne (AU)
- Walter and Eliza Hall Institute of Medical Research (AU)
- La Trobe University (AU)
- Australian Regenerative Medicine Institute (AU)
- Olivia Newton-John Cancer Wellness & Research Centre (AU)
- Monash University (AU)
Publication Details
- Journal
- BMC Genomics
- Published
- 2026-02-09
- DOI
- https://doi.org/10.1186/s12864-026-12596-z
- Primary Topic
- Parasites and Host Interactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00