A Wolf in the Jaw—“Pediatric Myofibroblastic Sarcoma Hanging from the Maxilla”: Low Grade, High Impact

REPORTwith indentations and small nucleoli.Focal mild-to-moderate nuclear atypia and occasional mitotic activity was noted.On immunohistochemical expression, tumor cells were immunopositive for Vimentin, SMA (focal) while myogenin, desmin, S100, ALK, CD34, EMA, and Pan-TRK were negative, favoring the diagnosis of LGMS (Fig. 3).The patient was then administered three doses of ifosfamide and doxorubicin, again with no appreciable tumor regression.Given the lack of response to chemotherapy, the case was referred 1-