Clinical Characteristics, Management, and Outcomes of Patients Living with HIV and Coinfected with Talaromyces marneffei and Cryptococcus: A Retrospective Case Series
Co-infection with <i>T. marneffei</i> and <i>Cryptococcus</i> in HIV patients is associated with nonspecific clinical presentations and high mortality. Elevated CSF LDH levels, particularly CSF LDH levels >21.15 U/L, are a significant risk factor for death. Early cryptococcal antigen screening and prompt antifungal therapy are crucial for improving outcomes in this population.
Authors
- Yanqing Zheng (ORCID: https://orcid.org/0000-0002-7809-5527)
- Zhiwen Jiang (ORCID: https://orcid.org/0000-0001-8841-618X)
- Yangni Lu
- Jun Zou
- Jianlin Wu
- Xiaoying Qin
- Maowei Chen
- Jianye Nai
Institutions
- Guangxi University (CN)
- Guangxi Medical University (CN)
- The Fourth People's Hospital (CN)
- First Affiliated Hospital of GuangXi Medical University (CN)
- The Second Nanning People's Hospital (CN)
- Guangxi Center for Disease Prevention and Control (CN)
- First People's Hospital of Nanning (CN)
- Second People’s Hospital of Yibin (CN)
Publication Details
- Journal
- Infection and Drug Resistance
- Published
- 2026-02-01
- DOI
- https://doi.org/10.2147/idr.s558689
- Primary Topic
- Fungal Infections and Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China