Placental transfer and vasoactivity of cannabidiol: beware of rapid oxidation
Rapid oxidation of CBD can be prevented by adding an antioxidant. Under those conditions, CBD transfers to the fetus. CBD dilates fetoplacental vessels, while THC induces constriction. These data may help to understand potential risks of cannabis use in pregnancy.
Authors
- S. Stoney Simons
- A.H.J. Danser
- Lisa Höfert (ORCID: https://orcid.org/0000-0001-8723-4405)
- Sven Baumann
- M.S. Harhangi
- M. Broekhuizen
- I.K.M. Reiss
Institutions
- Universität Hamburg (DE)
- Erasmus MC (NL)
- University Medical Center Hamburg-Eppendorf (DE)
- Leipzig University (DE)
Publication Details
- Journal
- European Journal of Pharmacology
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1016/j.ejphar.2026.178653
- Primary Topic
- Cannabis and Cannabinoid Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00