HLA Experts’ Perspectives on Precision Medicine and Molecular Matching in Kidney Transplantation: A Qualitative Study
This study highlights the complexities of integrating molecular matching into organ allocation, raising concerns about equity, feasibility, and implementation. While HLA experts agree on the importance of ensuring equity and timely access, their perspectives also underscore the challenges of implementation, such as the availability of timely high-resolution HLA typing, stakeholder buy-in, and the need for dedicated tools and applications. To ensure an ethical and equitable implementation, future efforts must address access disparities through targeted mitigation strategies, such as the introduction of a maximum waiting time for a molecular-matched kidney.
Authors
- Fabián Ballesteros
- Aliya Affdal (ORCID: https://orcid.org/0000-0001-8924-4308)
- Marcel Fortin
- Carina Sancho (ORCID: https://orcid.org/0000-0001-6433-5465)
- Marie‐Françoise Malo
- Savannah-Lou Cochran-Mavrikakis
- Lucy An
- Paul Keown
- Noémi Tousignant
- Stirling Bryan
- Ruth Sapir-Pichhadze
Institutions
- University of British Columbia (CA)
- McGill University Health Centre (CA)
- Translational Research in Oncology (CA)
- Centre Hospitalier de l’Université de Montréal (CA)
- Université de Montréal (CA)
Publication Details
- Journal
- Canadian Journal of Kidney Health and Disease
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1177/20543581251412195
- Primary Topic
- Renal Transplantation Outcomes and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00