HLA Experts’ Perspectives on Precision Medicine and Molecular Matching in Kidney Transplantation: A Qualitative Study

This study highlights the complexities of integrating molecular matching into organ allocation, raising concerns about equity, feasibility, and implementation. While HLA experts agree on the importance of ensuring equity and timely access, their perspectives also underscore the challenges of implementation, such as the availability of timely high-resolution HLA typing, stakeholder buy-in, and the need for dedicated tools and applications. To ensure an ethical and equitable implementation, future efforts must address access disparities through targeted mitigation strategies, such as the introduction of a maximum waiting time for a molecular-matched kidney.

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Publication Details

Journal
Canadian Journal of Kidney Health and Disease
Published
2026-02-01
DOI
https://doi.org/10.1177/20543581251412195
Primary Topic
Renal Transplantation Outcomes and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

HLA Experts’ Perspectives on Precision Medicine and Molecular Matching in Kidney Transplantation: A Qualitative Study

Fabián Ballesteros, Aliya Affdal, Marcel Fortin, Carina Sancho et al.
Canadian Journal of Kidney Health and Disease
Renal Transplantation Outcomes and Treatments
article

HLA Experts’ Perspectives on Precision Medicine and Molecular Matching in Kidney Transplantation: A Qualitative Study

Fabián Ballesteros, Aliya Affdal, Marcel Fortin, Carina Sancho, Marie‐Françoise Malo, Savannah-Lou Cochran-Mavrikakis, Lucy An, Paul Keown, Noémi Tousignant, Stirling Bryan, Ruth Sapir-Pichhadze
article en

Abstract

This study highlights the complexities of integrating molecular matching into organ allocation, raising concerns about equity, feasibility, and implementation. While HLA experts agree on the importance of ensuring equity and timely access, their perspectives also underscore the challenges of implementation, such as the availability of timely high-resolution HLA typing, stakeholder buy-in, and the need for dedicated tools and applications. To ensure an ethical and equitable implementation, future efforts must address access disparities through targeted mitigation strategies, such as the introduction of a maximum waiting time for a molecular-matched kidney.

Canadian Journal of Kidney Health and DiseaseVol. 13
University of British Columbia (CA), McGill University Health Centre (CA), Translational Research in Oncology (CA), Centre Hospitalier de l’Université de Montréal (CA), Université de Montréal (CA)
Openalex Percentile: Top 65%
Renal Transplantation Outcomes and Treatments
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