ROS-Responsive Nano-Encapsulated Selenium Targeting Cervical Cancer Cell via PI3K/AKT Signaling Pathway
This work confirms FA-ReRSeNPs as a precision-driven nanotherapeutic for cervical cancer management. The fusion of active targeting and ROS-responsive release mechanisms addresses the classic efficacy-toxicity dilemma of conventional anticancer agents, highlighting the translational value of intelligent nanoengineering in advancing cancer therapies.
Authors
- Jingjing Weng
- Yanmei Qiu
- Chongke Hu (ORCID: https://orcid.org/0009-0001-5517-0977)
- Lingling Zhao (ORCID: https://orcid.org/0000-0002-1532-7247)
- Jiaying Shen (ORCID: https://orcid.org/0009-0005-8418-2431)
- Shushu Zhao (ORCID: https://orcid.org/0000-0001-5265-9681)
- Yingying Zhu (ORCID: https://orcid.org/0000-0002-5366-974X)
- Fanjia Dai
- Fei Guo
- Xiaoping Huang
- Dezhi Chen
- Yimin Ma
- Mengxin Ban
Institutions
- Ningbo University (CN)
- Nanchang University (CN)
- First Affiliated Hospital of Jiangxi Medical College (CN)
- Ningbo Medical Center Lihuili Hospital (CN)
- First Affiliated Hospital of Nanchang University (CN)
Publication Details
- Journal
- International Journal of Nanomedicine
- Published
- 2026-02-01
- DOI
- https://doi.org/10.2147/ijn.s558115
- Primary Topic
- Selenium in Biological Systems
- Type
- article
- Field-Weighted Citation Impact
- 0.00