Treatment Challenges in Refractory Urticarial Vasculitis

Abstract: Urticarial vasculitis, a rare autoimmune disease, is characterized by inflammation of the small blood vessels. It presents with skin lesions that resemble hives, but unlike ordinary hives, these lesions last longer than 24 hours, may leave behind bruise-like discoloration or purpura, and can be associated with systemic symptoms. This case reports details a middle-aged female patient, who exhibited extensive urticarial lesions persisting for two weeks and severe reactions to initial treatments. Keywords: refractory urticarial vasculitis, omalizumab, immunosuppressants