Psychosocial outcomes after targeted muscle reinnervation in patients with neuropathic pain
Patients who underwent TMR for neuropathic pain management demonstrated improved psychosocial outcomes. Non-amputees and pTMR patients demonstrated greater improvements in depression and anxiety compared to sTMR patients. Sleep quality and duration improved substantially, a previously underreported benefit of TMR. Future, larger prospective studies should further validate relationship between neuropathic pain reduction through TMR and psychosocial outcomes.
Authors
- Ian L. Valerio (ORCID: https://orcid.org/0000-0001-8573-8810)
- Bárbara Gómez-Eslava (ORCID: https://orcid.org/0000-0002-1597-5519)
- William Renthal (ORCID: https://orcid.org/0000-0003-0206-2101)
- Tsong-Hann Yu
- Floris V. Raasveld (ORCID: https://orcid.org/0000-0002-7566-1159)
- J. E. Ho
- Maximilian Mayrhofer-Schmid
- David Hao
- Clifford J Woolf
- Kyle R Eberlin
Institutions
- Brigham and Women's Hospital (US)
- Boston Children's Hospital (US)
- Erasmus MC (NL)
- Massachusetts General Hospital (US)
- Unfallkrankenhaus Berlin (DE)
- Center for Pain and the Brain (US)
- National Defense Medical Center (TW)
- Erasmus University Rotterdam (NL)
Publication Details
- Journal
- Pain Medicine
- Published
- 2026-02-02
- DOI
- https://doi.org/10.1093/pm/pnag023
- Primary Topic
- Pain Management and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00