Heart Replacement Therapy in Young Patients

Contemporary data suggest that durable LVAD therapy may offer survival outcomes comparable to HT in adults <50 years of age. These findings support the consideration of an LVAD-first strategy as a viable initial approach to heart replacement therapy in appropriately selected patients. (Multicenter Study of MagLev Technology in Patients Undergoing Mechanical Circulatory Support Therapy with HeartMate 3 Investigational Device Exemption [MOMENTUM 3 IDE]; NCT02224755) (MOMENTUM 3 Continued Access Protocol [MOMENTUM 3 CAP]; NCT02892955).

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Publication Details

Journal
JACC Heart Failure
Published
2026-02-01
DOI
https://doi.org/10.1016/j.jchf.2026.102948
Citations
1
Primary Topic
Mechanical Circulatory Support Devices
Type
article
Field-Weighted Citation Impact
21.28
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article

Heart Replacement Therapy in Young Patients

F. Lee, B. Elad, D. Lotan, Justin Fried et al.
1 citations
JACC Heart Failure
Mechanical Circulatory Support Devices
21.28
article

Heart Replacement Therapy in Young Patients

F. Lee, B. Elad, D. Lotan, Justin Fried, Joseph C Cleveland, Jayant K Raikhelkar, Stavros G Drakos, Gabriel T Sayer, Kevin J Clerkin, Manreet K Kanwar, Daniel J Goldstein, Mandeep R Mehra, Katherine L Wood, Nir Uriel, John D Henderson
article en
1 citations

Abstract

Contemporary data suggest that durable LVAD therapy may offer survival outcomes comparable to HT in adults <50 years of age. These findings support the consideration of an LVAD-first strategy as a viable initial approach to heart replacement therapy in appropriately selected patients. (Multicenter Study of MagLev Technology in Patients Undergoing Mechanical Circulatory Support Therapy with HeartMate 3 Investigational Device Exemption [MOMENTUM 3 IDE]; NCT02224755) (MOMENTUM 3 Continued Access Protocol [MOMENTUM 3 CAP]; NCT02892955).

JACC Heart Failure
Brigham and Women's Hospital (US), Albert Einstein College of Medicine (US), Montefiore Medical Center (US), University of Utah (US), Columbia University Irving Medical Center (US), University of Chicago (US), University of California, Irvine Medical Center (US), Abbott Fund (US), University of Colorado Anschutz Medical Campus (US), University of Colorado Denver (US)
Openalex Percentile: Top 1%
Mechanical Circulatory Support Devices
21.28
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Heart Replacement Therapy in Young Patients — F. Lee, B. Elad, et al. · JACC Heart Failure (2026) | TGRS Research Map | TGRS