Impact of Hypobaria and Hypoxia Exposure on Mortality, Inflammation, and Coagulopathy in an Animal Model of Polytrauma
The polytrauma model induces marked circulatory dysfunction, systemic inflammation, thrombocytopenia, and hypercoagulation in mice. Hypobaria and hypoxia exposure further increased mortality, circulatory dysfunction, and inflammation following polytrauma.
Authors
- Bryan Williams (ORCID: https://orcid.org/0000-0002-8094-1841)
- Xiaomei Yang (ORCID: https://orcid.org/0009-0002-1105-789X)
- Wei Chao (ORCID: https://orcid.org/0000-0002-6666-5801)
- Zou Li
- Chanhee Park
- Fengqian Chen
- John Kessler II
- Arijit Duta
Institutions
- University of Maryland, Baltimore (US)
Publication Details
- Journal
- Military Medicine
- Published
- 2026-01-21
- DOI
- https://doi.org/10.1093/milmed/usag021
- Primary Topic
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Type
- article
- Field-Weighted Citation Impact
- 0.00