Radical antegrade modular pancreatosplenectomy <i>versus</i> conventional left pancreatectomy for pancreatic cancer: study protocol for the multicentre randomized clinical RAMPS trial

The primary objective of the RAMPS trial is to demonstrate the superiority of the RAMPS approach over standard left pancreatectomy in improving the achievement of R0 resection and, consequently, long-term oncological patient outcomes. RAMPS could be established as the new surgical standard for tumour resection in patients with pancreatic cancer in the body or tail of the pancreas. Registration number: DRKS00033031 (https://www.bfarm.de/EN/BfArM/Tasks/German-Clinical-Trials-Register/_node.html).

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Publication Details

Journal
BJS Open
Published
2025-12-13
DOI
https://doi.org/10.1093/bjsopen/zraf169
Primary Topic
Pancreatic and Hepatic Oncology Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Radical antegrade modular pancreatosplenectomy versus conventional left pancreatectomy for pancreatic cancer: study protocol for the multicentre randomized clinical RAMPS trial

Markus K. Diener, Christina Klose, Magdalena Holze, Frank Pianka et al.
BJS Open
Pancreatic and Hepatic Oncology Research
article

Radical antegrade modular pancreatosplenectomy versus conventional left pancreatectomy for pancreatic cancer: study protocol for the multicentre randomized clinical RAMPS trial

Markus K. Diener, Christina Klose, Magdalena Holze, Frank Pianka, Felix J. Hüttner, M Wittmann, Solveig Tenckhoff, Ines Photiadis, Anja Sander, Patrick Heger, Mohammed Al-Saeedi, Rosa Klotz, Markus W Büchler, Christoph W Michalski, Thilo Hackert, Martin Loos, Alexandra Balzer
article en

Abstract

The primary objective of the RAMPS trial is to demonstrate the superiority of the RAMPS approach over standard left pancreatectomy in improving the achievement of R0 resection and, consequently, long-term oncological patient outcomes. RAMPS could be established as the new surgical standard for tumour resection in patients with pancreatic cancer in the body or tail of the pancreas. Registration number: DRKS00033031 (https://www.bfarm.de/EN/BfArM/Tasks/German-Clinical-Trials-Register/_node.html).

BJS OpenVol. 10(1)
Champalimaud Foundation (PT), German Society of Surgery (DE), Universität Hamburg (DE), Zimmer Biomet (Netherlands) (NL), Heidelberg University (DE), University Hospital Heidelberg (DE), Nuremberg Hospital (DE), University Medical Center Hamburg-Eppendorf (DE)
Openalex Percentile: Top 27%
Pancreatic and Hepatic Oncology Research
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