Histopathological Findings of Appendix Specimens in Quiescent Ulcerative Colitis: Correlations With Clinical Outcomes in the ACCURE Trial

Active appendiceal inflammation is prevalent in quiescent UC and showed a trend toward association with relapse risk. Although the benefit of appendicectomy in this group cannot be confirmed on these data alone, the finding might be clinically relevant as relapse rates are significantly reduced in the appendicectomy group.

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Publication Details

Journal
United European Gastroenterology Journal
Published
2026-02-01
DOI
https://doi.org/10.1002/ueg2.70177
Primary Topic
Appendicitis Diagnosis and Management
Type
article
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article

Histopathological Findings of Appendix Specimens in Quiescent Ulcerative Colitis: Correlations With Clinical Outcomes in the ACCURE Trial

Lianne Heuthorst, Aart Mookhoek, C J Buskens, Willem A Bemelman et al.
United European Gastroenterology Journal
Appendicitis Diagnosis and Management
article

Histopathological Findings of Appendix Specimens in Quiescent Ulcerative Colitis: Correlations With Clinical Outcomes in the ACCURE Trial

Lianne Heuthorst, Aart Mookhoek, C J Buskens, Willem A Bemelman, Demy Danielsson, Eva Visser, Geert R D'Haens
article en

Abstract

Active appendiceal inflammation is prevalent in quiescent UC and showed a trend toward association with relapse risk. Although the benefit of appendicectomy in this group cannot be confirmed on these data alone, the finding might be clinically relevant as relapse rates are significantly reduced in the appendicectomy group.

United European Gastroenterology JournalVol. 14(1)
University of Bern (CH), Amsterdam University Medical Centers (NL), University of Amsterdam (NL)
Good health and well-being
Openalex Percentile: Top 65%
Appendicitis Diagnosis and Management
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