IMIQUIMOD – IMMUNE RESPONSE MODIFIER

Imiquimod is a low molecular weight compound acting as a local immune response modifier and activating factors of both inborn and acquired immunity (especially T-helpers 1), causing antiviral, antitumor and immunoregulatory effects. It stimulates TLR-7/8 receptors, triggering the immune response mechanisms. It is used in dermatology for the treatment of diseases caused by human papillomavirus and has various antiproliferative and immunomodulatory effects. It is also used for reproduction of the mouse models of psoriasis.

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Journal
Медицинский вестник МВД
Published
2024-12-24
DOI
https://doi.org/10.52341/20738080_2024_133_6_42
Primary Topic
Psoriasis: Treatment and Pathogenesis
Type
article
Field-Weighted Citation Impact
0.00
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article

IMIQUIMOD – IMMUNE RESPONSE MODIFIER

О. А. Свитич, E. KALINIChENKO, E. SOROKINA, E. AHMATOVA
Медицинский вестник МВД
Psoriasis: Treatment and Pathogenesis
article

IMIQUIMOD – IMMUNE RESPONSE MODIFIER

О. А. Свитич, E. KALINIChENKO, E. SOROKINA, E. AHMATOVA
article en

Abstract

Imiquimod is a low molecular weight compound acting as a local immune response modifier and activating factors of both inborn and acquired immunity (especially T-helpers 1), causing antiviral, antitumor and immunoregulatory effects. It stimulates TLR-7/8 receptors, triggering the immune response mechanisms. It is used in dermatology for the treatment of diseases caused by human papillomavirus and has various antiproliferative and immunomodulatory effects. It is also used for reproduction of the mouse models of psoriasis.

Медицинский вестник МВДVol. 2024(6)
Sechenov University (RU), Research Institute of Vaccines and Sera. Mechnikov of the Russian Academy of Medical Sciences (RU), Medical Technologies (Czechia) (CZ)
Good health and well-being
Openalex Percentile: Top 48%
Psoriasis: Treatment and Pathogenesis
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