IMIQUIMOD – IMMUNE RESPONSE MODIFIER
Imiquimod is a low molecular weight compound acting as a local immune response modifier and activating factors of both inborn and acquired immunity (especially T-helpers 1), causing antiviral, antitumor and immunoregulatory effects. It stimulates TLR-7/8 receptors, triggering the immune response mechanisms. It is used in dermatology for the treatment of diseases caused by human papillomavirus and has various antiproliferative and immunomodulatory effects. It is also used for reproduction of the mouse models of psoriasis.
Authors
- О. А. Свитич (ORCID: https://orcid.org/0000-0003-1757-8389)
- E. KALINIChENKO
- E. SOROKINA
- E. AHMATOVA
Institutions
- Sechenov University (RU)
- Research Institute of Vaccines and Sera. Mechnikov of the Russian Academy of Medical Sciences (RU)
- Medical Technologies (Czechia) (CZ)
Publication Details
- Journal
- Медицинский вестник МВД
- Published
- 2024-12-24
- DOI
- https://doi.org/10.52341/20738080_2024_133_6_42
- Primary Topic
- Psoriasis: Treatment and Pathogenesis
- Type
- article
- Field-Weighted Citation Impact
- 0.00