Neurofilament Light Chain in Fibromyalgia: Correlation With Central and Peripheral Nervous System Dysfunction
These findings support the concept of FM as a neurogenic disorder and suggest serum NfL as a potential biomarker of neuronal stress in chronic pain, although it is not specific for peripheral nerve damage or cognitive dysfunction.
Authors
- Giulia Paparella (ORCID: https://orcid.org/0000-0002-7760-9442)
- Concetta Domenica Gargano
- Maddalena Ruggieri (ORCID: https://orcid.org/0000-0001-7419-570X)
- Livio Clemente (ORCID: https://orcid.org/0000-0001-5463-0460)
- Grazia Devigili (ORCID: https://orcid.org/0000-0001-9688-4231)
- Giuseppe Lauria
- Marina de Tommaso
Institutions
- Istituto Neurologico Mediterraneo (IT)
- Fondazione IRCCS Istituto Neurologico Carlo Besta (IT)
- University of Bari Aldo Moro (IT)
Publication Details
- Journal
- European Journal of Pain
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1002/ejp.70228
- Primary Topic
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00