Proteomics reveals three molecular subtypes of Alzheimer's disease with distinct progression patterns
These findings demonstrate robust, biologically distinct AD subtypes linked to divergent molecular pathways, clinical features, and progression rates. Such refined stratification supports precision diagnostics and targeted therapeutic strategies.
Authors
- Jian‐feng Feng
- Fei Xie (ORCID: https://orcid.org/0000-0003-2891-3883)
- Wei Cheng (ORCID: https://orcid.org/0000-0002-5297-7046)
- Jingwei Yu (ORCID: https://orcid.org/0000-0002-7587-754X)
- Yifei Jin (ORCID: https://orcid.org/0009-0008-2817-2791)
- Linbo Wang (ORCID: https://orcid.org/0000-0002-6982-103X)
- Wen Zhang (ORCID: https://orcid.org/0000-0001-5166-0736)
- Bei Zhang (ORCID: https://orcid.org/0000-0003-0845-7534)
- Jia You
- K. Kang (ORCID: https://orcid.org/0009-0006-2376-534X)
- Zeyu Li
- Yuzhu Li
- Xiao‐He Hou
- Qing Ma
- Peng Ren
- for the Alzheimer's Disease Neuroimaging Initiative
Institutions
- Qingdao University (CN)
- Zhejiang Normal University (CN)
- Fudan University (CN)
- University of Warwick (GB)
- Qingdao Municipal Hospital (CN)
- Huashan Hospital (CN)
- Shanghai Center for Brain Science and Brain-Inspired Technology (CN)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1002/alz.71106
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00