Nine-Year Trends in Antibiotic Resistance of Culture-Proven Pseudomonas aeruginosa Keratitis at a Tertiary Eye Center

Over 9 years, Pseudomonas aeruginosa isolates retained sensitivity to older fluoroquinolones and aminoglycosides, while there was a trend toward increasing resistance to moxifloxacin. Cephalosporin and beta-lactam resistance remained high, except for ceftazidime and piperacillin-tazobactam. Despite the limitations of the study, these findings support a continued role for ciprofloxacin and aminoglycosides as empiric therapy options.