Radioactive Distribution Patterns of [68Ga]Ga-FAPI-04 in Primary Hepatocellular Carcinoma
[ 68 Ga]Ga-FAPI-04 PET/CT demonstrated higher marginal uptake and pronounced central heterogeneity (low-SUV centers) in HCC. Strong peripheral uptake supports the use of FAP-targeted fluorescence-guided surgery and targeted treatment of marginal residual/recurrent disease, while low central uptake may limit FAP-targeted therapy.
Authors
- Yuankai Zhu (ORCID: https://orcid.org/0000-0003-2219-251X)
- Dongling Zhu
- Qingjian Dong
- Sijuan Zou
- Dong Kuang
- Xiaohua Zhu
- Shuang Song
Institutions
- Tongji Hospital (CN)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- Clinical Nuclear Medicine
- Published
- 2026-02-02
- DOI
- https://doi.org/10.1097/rlu.0000000000006345
- Primary Topic
- Peptidase Inhibition and Analysis
- Type
- article
- Field-Weighted Citation Impact
- 0.00