Sychronous and metachronous primary malignant neoplasm of the urogenital organs our recent experience

Synchronous malignant infections occur in two or more primary neoplasms that occur continuously or at different intervals in the same patient. According to the time of occurrence, they can be divided into so-called simultaneous multiple so-called synchronous small neoplasms that occur within 6 months, and multiple hetero small neoplasms that occur at an interval of more than 6 months (1). According to the studies published so far, synchronous small neoplasms of different generation of origin can be considered the same between organs or controls of different or different organ systems. The most common reasons for their occurrence include: increasingly advanced screening diagnostic methods, genetic defects, reduced immunity due to receiving oncological therapy, the inflence of one of the malignant processes, congenital or acquired diabetes, chronic renal failure, environmental inflences, etc. (2). The prevalence rate of such two or more synchronous primary neoplasms is estimated at 4.5% to 11.7%. In most cases, over 75% of diagnosed patients belong to the population group older than 50 years. Men are more affected than women in terms of synchronous and metachronous neoplastic phenomena (3). The treatment is most often multimodal, which simultaneously includes surgical, oncological and radiological treatment approaches.