Optimal Use Recommendations and Stewardship Principles with Oral Antibiotics in Acne Vulgaris Management: An Expert Consensus Panel.

The expert panel concluded that oral antibiotics can be used in the treatment of moderate-to-severe AV, oral antibiotics should be combined with topical treatments, and duration of use should be determined based on individualized patient care. Tetracyclines are recognized options for AV therapy, with sarecycline considered a preferred option for AV due to its targeted mode of action, unique ribosomal binding properties, narrow spectrum of antibiotic activity, lower bacterial resistance risk, and overall better tolerability. Additionally, tetracyclines should be avoided in pregnancy and in young children.

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Journal
PubMed
Published
2025-12-01
Primary Topic
Acne and Rosacea Treatments and Effects
Type
article
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article

Optimal Use Recommendations and Stewardship Principles with Oral Antibiotics in Acne Vulgaris Management: An Expert Consensus Panel.

Evan A. Rieder, L. Stein Gold, Lauren E DeBusk, Julie Harper et al.
PubMed
Acne and Rosacea Treatments and Effects
article

Optimal Use Recommendations and Stewardship Principles with Oral Antibiotics in Acne Vulgaris Management: An Expert Consensus Panel.

Evan A. Rieder, L. Stein Gold, Lauren E DeBusk, Julie Harper, Joshua Burshtein, Pearl Kwong, Danny Zakria, Adelaide A. Hebert, Brooke Bartley, Hilary E. Baldwin, Milaan Milaan Shah, Jonette Keri, Angela Rosenberg, James Q Del Rosso
article en

Abstract

The expert panel concluded that oral antibiotics can be used in the treatment of moderate-to-severe AV, oral antibiotics should be combined with topical treatments, and duration of use should be determined based on individualized patient care. Tetracyclines are recognized options for AV therapy, with sarecycline considered a preferred option for AV due to its targeted mode of action, unique ribosomal binding properties, narrow spectrum of antibiotic activity, lower bacterial resistance risk, and overall better tolerability. Additionally, tetracyclines should be avoided in pregnancy and in young children.

PubMedVol. 18(12)
Robert Wood Johnson University Hospital (US), Memorial Hermann (US), University of Miami (US), Medical University of South Carolina (US), Henry Ford Hospital (US), University of Illinois Chicago (US), University of Chicago (US), Southwestern Medical Center (US), IS practice (BE), Skin Research Center (FR), Gold Skin Care Center (US), Touro University Nevada (US), The University of Texas Southwestern Medical Center (US), Icahn School of Medicine at Mount Sinai (US)
Good health and well-being
Openalex Percentile: Top 21%
Acne and Rosacea Treatments and Effects
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