The limited clinical utility of neutrophil-to-lymphocyte ratio in systemic lupus erythematosus: A meta-analysis with external validation
NLR is elevated in SLE, LN, and active disease, showing a weak positive correlation with disease activity. However, its clinical utility is influenced by ethnicity and treatment, indicating that it should not be used as an independent biomarker but may have a role as part of a combined assessment.
Authors
- Wanxin Tang (ORCID: https://orcid.org/0009-0002-0375-4185)
- L Q Chen
- Xiangping Tu
- Mengfei Li
- Yongdi Zuo
- Manrong He
- Jingxue Du
Institutions
- Sichuan University (CN)
- West China Hospital of Sichuan University (CN)
Publication Details
- Journal
- Human Immunology
- Published
- 2026-02-05
- DOI
- https://doi.org/10.1016/j.humimm.2026.111683
- Primary Topic
- Systemic Lupus Erythematosus Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00