Cryobiopsy in the Diagnosis of Pulmonary Vein Stenosis After Catheter Ablation of Atrial Fibrillation: A Case Report

Pulmonary vein stenosis-a complication of atrial fibrillation ablation unfamiliar to most pulmonologists-was identified in a 42-year-old man who presented with haemoptysis. Initial bronchoscopy at a previously visited hospital revealed a central airway lesion, but biopsy was declined because of its haemorrhagic nature. Repeat bronchoscopy at our hospital showed oedematous changes and vascular proliferation in the left main bronchus, suggesting adenoid cystic carcinoma. However, cryobiopsy excluded malignancy and suggested a vascular malformation with thickened, irregularly dilated muscular vessels. Contrast-enhanced CT revealed occlusion of the left superior pulmonary vein, interpreted as a secondary change. The patient had a history of catheter ablation for atrial fibrillation. Based on these findings, the stenosis was determined to be a complication of catheter ablation, and surgical bypass was performed. Severe pulmonary vein stenosis was successfully diagnosed using cryobiopsy. This condition is unfamiliar to pulmonologists; however, differentiation from airway tumours is crucial for determining treatment.

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Journal
Respirology Case Reports
Published
2026-02-01
DOI
https://doi.org/10.1002/rcr2.70499
Primary Topic
Cardiac tumors and thrombi
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article
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article

Cryobiopsy in the Diagnosis of Pulmonary Vein Stenosis After Catheter Ablation of Atrial Fibrillation: A Case Report

Kenya Sato, Takaaki Tsuchida, Hideaki Furuse, Yuji Matsumoto
Respirology Case Reports
Cardiac tumors and thrombi
article

Cryobiopsy in the Diagnosis of Pulmonary Vein Stenosis After Catheter Ablation of Atrial Fibrillation: A Case Report

Kenya Sato, Takaaki Tsuchida, Hideaki Furuse, Yuji Matsumoto
article en

Abstract

Pulmonary vein stenosis-a complication of atrial fibrillation ablation unfamiliar to most pulmonologists-was identified in a 42-year-old man who presented with haemoptysis. Initial bronchoscopy at a previously visited hospital revealed a central airway lesion, but biopsy was declined because of its haemorrhagic nature. Repeat bronchoscopy at our hospital showed oedematous changes and vascular proliferation in the left main bronchus, suggesting adenoid cystic carcinoma. However, cryobiopsy excluded malignancy and suggested a vascular malformation with thickened, irregularly dilated muscular vessels. Contrast-enhanced CT revealed occlusion of the left superior pulmonary vein, interpreted as a secondary change. The patient had a history of catheter ablation for atrial fibrillation. Based on these findings, the stenosis was determined to be a complication of catheter ablation, and surgical bypass was performed. Severe pulmonary vein stenosis was successfully diagnosed using cryobiopsy. This condition is unfamiliar to pulmonologists; however, differentiation from airway tumours is crucial for determining treatment.

Respirology Case ReportsVol. 14(2)
National Cancer Center Hospital East (JP)
Good health and well-being
Openalex Percentile: Top 65%
Cardiac tumors and thrombi
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Cryobiopsy in the Diagnosis of Pulmonary Vein Stenosis After Catheter Ablation of Atrial Fibrillation: A Case Report — Kenya Sato, Takaaki Tsuchida, et al. · Respirology Case Reports (2026) | TGRS Research Map | TGRS