Evaluation of DMSO-free cryopreservation reagent XT-Thrive for establishment of mesenchymal stem cell bank platform
XT-Thrive provides superior pre-freeze stability, post-thaw recovery, expansion potential, and osteogenic functionality compared to CS10, while maintaining MSC identity and genomic stability. These results support XT-Thrive as a promising DMSO-free alternative for clinical-grade MSC biobanking and manufacturing.
Authors
- Xiaoxi Wei (ORCID: https://orcid.org/0000-0002-4387-9161)
- Arthi Shridhar
- J. Lee
- Alan Tin-Lun Lam
- Harish K. Handral
- Steve Oh
Institutions
- Agency for Science, Technology and Research (SG)
- X Therma (US)
- Bioprocessing Technology Institute (SG)
- VinUniversity (VN)
Publication Details
- Journal
- Frontiers in Bioengineering and Biotechnology
- Published
- 2026-02-05
- DOI
- https://doi.org/10.3389/fbioe.2026.1736526
- Primary Topic
- Mesenchymal stem cell research
- Type
- article
- Field-Weighted Citation Impact
- 0.00