Cardiovascular risk profile of low-dose prednisolone and its effect on the quality of life in patients with adrenal insufficiency: the HYPER-AID observational study
Low-dose once-daily prednisolone offers comparable cardiovascular risk to hydrocortisone while improving treatment convenience, systolic blood pressure, and SF-36 subjective energy scores. These findings support the use of prednisolone as a potentially preferable alternative in patients with adrenal insufficiency.
Authors
- Kavita Narula (ORCID: https://orcid.org/0000-0002-7453-9039)
- Katharine Lazarus (ORCID: https://orcid.org/0000-0003-0758-7839)
- Sirazum Choudhury (ORCID: https://orcid.org/0000-0003-2429-005X)
- Zin Htut
- Milly Newham
- Karim Meeran
- Thozhukat Sathyapalan
Institutions
- Imperial College Healthcare NHS Trust (GB)
- University of Hull (GB)
- North West London Pathology (GB)
- Imperial College London (GB)
Publication Details
- Journal
- Endocrine Connections
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1530/ec-25-0904
- Primary Topic
- Adrenal Hormones and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00