Sex-specific phenotypes and outcomes in non‑IPF interstitial lung disease: results from the INSIGHTS‑ILD registry

Men and women with non-IPF ILD differ in exposures, phenotypes, and comorbidities, but after accounting for these factors, sex is not an independent predictor of survival or functional progression. Risk assessment should therefore primarily be based on objective disease characteristics rather than sex alone.

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Publication Details

Journal
Respiration
Published
2026-02-05
DOI
https://doi.org/10.1159/000550780
Primary Topic
Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
Type
article
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article

Sex-specific phenotypes and outcomes in non‑IPF interstitial lung disease: results from the INSIGHTS‑ILD registry

Daniel Grund, Stephan Eisenmann, Ralf Ewert, Peter Schramm et al.
Respiration
Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
article

Sex-specific phenotypes and outcomes in non‑IPF interstitial lung disease: results from the INSIGHTS‑ILD registry

Daniel Grund, Stephan Eisenmann, Ralf Ewert, Peter Schramm, M. Aringer, Tim Oqueka, Tobias Veit, Ekaterina Krauss, Marion Frankenberger, Werner von Wulffen, Stephan Walterspacher, Michael Westhoff, Bernd Seese, D Pittrow, Claus-Peter Kreutz, Sabine Haberl, B. Stubbe, Claus Neurohr, Elaine Koch, Ioana Sorina Andreica, Antje Prasse, Heike Biller, T Witte, Christine Pausch, Lars Hagmeyer, Sven Gläser, Markus Polke, Benjamin Seeliger, Jürgen Behr, Martin Schwaiblmair, Dirk Skowasch, Wolfgang Gesierich, Marlene Hechtner, Frank Reichenberger, Julia Wälscher, Christian Grohé, Hubert Wirtz, Joachim Meyer, Francesco Bonella, Michael Kreuter, Stephan Budweiser, Ulrich Neff, Dirk Koschel, Achim Grünewaldt, Andreas Günther, Michael E. Weber, Michael Dreher, Maximilian Malfertheiner
article en

Abstract

Men and women with non-IPF ILD differ in exposures, phenotypes, and comorbidities, but after accounting for these factors, sex is not an independent predictor of survival or functional progression. Risk assessment should therefore primarily be based on objective disease characteristics rather than sex alone.

Respiration
Good health and well-being
Openalex Percentile: Top 66%
Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
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