Biliopancreatic diversion with duodenal switch improve polycystic ovary syndrome with decreased serum ceramides
Our study showed the improvement of insulin resistance in PCOS models after BPD/DS with decreased serum ceramides. The sequestrant of bile acid reversed the improvement of insulin resistance with higher ceramides level.
Authors
- Xiaochuan Li (ORCID: https://orcid.org/0000-0002-6903-9574)
- Dalin Wu (ORCID: https://orcid.org/0000-0002-5757-5062)
- H. Chen
- Pengyu Li (ORCID: https://orcid.org/0000-0002-9879-6013)
- Mengdi Wang (ORCID: https://orcid.org/0000-0002-2101-9507)
- Weijie Chen (ORCID: https://orcid.org/0009-0005-4032-3482)
- Juan Liu
Institutions
- Academy of Medical Sciences (GB)
- Sun Yat-sen University (CN)
- Shenzhen University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking Union Medical College Hospital (CN)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2026-02-05
- DOI
- https://doi.org/10.3389/fendo.2026.1720242
- Primary Topic
- Ovarian function and disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Peking Union Medical College Hospital
- Peking Union Medical College
- Division of Graduate Education