Probiotic Bifidobacterium Confers Protection Against Heat Stroke Through Enhancement of Intestinal Barrier Function in Rats
Bifidobacterium pretreatment conferred significant multiorgan protection and reduced systemic inflammation in HS rats. The core protective mechanism involves preserving intestinal mucosal barrier function. Maintaining intestinal mucosal barrier integrity may represent a promising strategy for the prevention of HS and the mitigation of associated systemic inflammatory responses and multiple organ dysfunction syndrome.
Authors
- Jingyi Huang (ORCID: https://orcid.org/0000-0002-1209-9699)
- Jingping Cai
- Guizhi Xia
- Xiaojing Nie
- Qiuping Fan
- Jie Chen (ORCID: https://orcid.org/0000-0003-3435-0351)
- Guimei Cai
- Yuehua Chen (ORCID: https://orcid.org/0009-0006-1343-7449)
- Yuxian Tang (ORCID: https://orcid.org/0009-0001-4179-0446)
- Yunfan Zhang (ORCID: https://orcid.org/0009-0004-4101-2507)
- Chengfeng Wang
- Ai Feng
- Jing Zhang
Institutions
- Fujian Medical University (CN)
- Xiamen University (CN)
- 117th Hospital of People's Liberation Army (CN)
- Zhongshan Hospital of Xiamen University (CN)
Publication Details
- Journal
- Shock
- Published
- 2026-02-02
- DOI
- https://doi.org/10.1097/shk.0000000000002805
- Primary Topic
- Thermoregulation and physiological responses
- Type
- article
- Field-Weighted Citation Impact
- 0.00