Clinical experience with metagenomic next-generation sequencing (mNGS) for the detection of Tropheryma whipplei in respiratory specimens: A multicenter retrospective observational study
The application of mNGS on respiratory specimens stands as an exceptional diagnostic modality, proficient in identifying rare microbial infections, exemplified by those induced by T. whipplei. Future research should launch prospective trials to optimize regimens, assess outcomes, and track long-term survival precisely.
Authors
- H. Wang
- Jian Fang (ORCID: https://orcid.org/0000-0002-1077-3686)
- Shan Wang (ORCID: https://orcid.org/0000-0002-7971-8300)
- Zhenpeng Li (ORCID: https://orcid.org/0000-0001-9431-258X)
- Lingxiao Sun
- Yifan Guo
- Hongbin Chen
- Bin Cao
- Qi Wang
- Yuyao Yin
Institutions
- Peking University (CN)
- Wenzhou Medical University (CN)
- China-Japan Friendship Hospital (CN)
- Peking University People's Hospital (CN)
- Anhui Academy of Coal Science (CN)
Publication Details
- Journal
- International Journal of Infectious Diseases
- Published
- 2026-02-05
- DOI
- https://doi.org/10.1016/j.ijid.2026.108457
- Primary Topic
- Whipple's Disease and Interleukins
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China