In vitro effects of different biomaterials on canine dental pulp stem cells
MTA, RS+, and CF demonstrated overall biocompatibility with cDPSCs and supported odontogenic differentiation under clinically relevant conditions. CF exhibited the lowest acute cytotoxicity, indicating its potential as a carrier for DPSC-based regenerative endodontic applications. These findings support the translational importance of <i>in vitro</i> cDPSC models for evaluating biomaterial performance in veterinary regenerative endodontics.
Authors
- Ana Nemec
- Andraž Kocjan (ORCID: https://orcid.org/0000-0002-4726-2775)
- Metka Voga (ORCID: https://orcid.org/0009-0007-6708-2855)
- Robert Marx
Institutions
- University of Hohenheim (DE)
- University of Ljubljana (SI)
- Jožef Stefan Institute (SI)
- Institute for Animal Reproduction (JP)
Publication Details
- Journal
- Frontiers in Veterinary Science
- Published
- 2026-02-05
- DOI
- https://doi.org/10.3389/fvets.2026.1758525
- Primary Topic
- Endodontics and Root Canal Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00