Double dissociation between conduction aphasia and conduction agraphia supports a ventro‐dorsal partition of the left arcuate fasciculus
We identified in two awake surgery cases a postoperative double dissociation between phonological and graphemic output buffer deficits. Using lesion-symptom mapping from ischaemic mini-strokes and preoperative tractography, we demonstrated that the phonological (resp. graphemic) disorder fitted with ventral (resp. dorsal) damage to the AF. Further studies are needed to confirm our hypothesis of a ventro-dorsal functional organization within the AF for phonological versus graphemic processing.
Authors
- Francine Chassoux (ORCID: https://orcid.org/0000-0002-1970-6578)
- Bertrand Devaux (ORCID: https://orcid.org/0000-0002-0628-3078)
- Isabelle Poisson
- Valéry Mandonnet
- Sébastien Froelich (ORCID: https://orcid.org/0000-0001-9124-2395)
- Emmanuel Mandonnet (ORCID: https://orcid.org/0000-0003-0230-9282)
Institutions
- Centre National de la Recherche Scientifique (FR)
- Inserm (FR)
- Université Paris Cité (FR)
- Hôpital Lariboisière (FR)
- Institut de Psychiatrie et Neurosciences de Paris (FR)
Publication Details
- Journal
- Journal of Neuropsychology
- Published
- 2026-02-05
- DOI
- https://doi.org/10.1111/jnp.70032
- Primary Topic
- Neurobiology of Language and Bilingualism
- Type
- article
- Field-Weighted Citation Impact
- 0.00