Associations between self-reported oral health and incident stroke: a prospective analysis of the UK Biobank

This study aims to explore whether different types of oral conditions are associated with incident stroke risk. This cohort study included 476,868 individuals without outcome events at baseline, multivariable models were constructed using Cox proportional hazard regression to assess the association between different oral conditions and the incidence of stroke, ischemic stroke (IS) and myocardial infarction (MI). Our fully adjusted model showed that individuals with painful gums [HRpainful gums: 1.31 (1.06, 1.63)], loose teeth [HRloose teeth: 1.45 (1.20, 1.77)] and dentures [HRdentures: 1.23 (1.12, 1.36)] have increased risk for stroke incidence. Individuals with painful gums, loose teeth and dentures have increased risk for stroke, IS and MI incidence, this study helps to identify high-risk stroke participants.

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Publication Details

Journal
BMC Public Health
Published
2026-02-05
DOI
https://doi.org/10.1186/s12889-026-26397-2
Primary Topic
Oral microbiology and periodontitis research
Type
article
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article

Associations between self-reported oral health and incident stroke: a prospective analysis of the UK Biobank

R. Y. Zhang, Huimin Liu, Mengting Liu, Jianzhong Chen et al.
BMC Public Health
Oral microbiology and periodontitis research
article

Associations between self-reported oral health and incident stroke: a prospective analysis of the UK Biobank

R. Y. Zhang, Huimin Liu, Mengting Liu, Jianzhong Chen, Qian-Yu Zhou, Peng Wang, Chang-Qing Sun, Hua Ye
article en

Abstract

This study aims to explore whether different types of oral conditions are associated with incident stroke risk. This cohort study included 476,868 individuals without outcome events at baseline, multivariable models were constructed using Cox proportional hazard regression to assess the association between different oral conditions and the incidence of stroke, ischemic stroke (IS) and myocardial infarction (MI). Our fully adjusted model showed that individuals with painful gums [HRpainful gums: 1.31 (1.06, 1.63)], loose teeth [HRloose teeth: 1.45 (1.20, 1.77)] and dentures [HRdentures: 1.23 (1.12, 1.36)] have increased risk for stroke incidence. Individuals with painful gums, loose teeth and dentures have increased risk for stroke, IS and MI incidence, this study helps to identify high-risk stroke participants.

BMC Public HealthVol. 26(1)
Zhengzhou University (CN), First Affiliated Hospital of Zhengzhou University (CN)
Good health and well-being
Openalex Percentile: Top 64%
Oral microbiology and periodontitis research
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