The Significance of Combined Detection of Ultrasonography, Pediatric Appendicitis Score, and C-Reactive Protein in the Diagnosis and Pathological Type of Acute Appendicitis in Children

This study investigates the diagnostic efficacy of combining ultrasonography, Pediatric Appendicitis Score (PAS), and C-reactive protein (CRP) for appendicitis in children. We retrospectively analyzed 268 children with acute abdominal pain from 2017 to 2020. Compared with those of any single diagnostic method, the sensitivity and negative predictive value of ultrasonography combined with the pediatric appendicitis score and C-reactive protein were higher in diagnosing acute appendicitis (<i>P</i> < .05). In addition, the sensitivity of ultrasonography combined with C-reactive protein was also greater for diagnosing acute complicated appendicitis (<i>P</i> < .05). Ultrasonography correlated closely with pathological examination findings for appendicitis types (Kappa = 0.888; <i>P</i> < .05). The combined use of ultrasonography, the Pediatric Appendicitis Score, and C-reactive protein enhances the diagnostic accuracy for acute appendicitis. Furthermore, the integration of ultrasonography with C-reactive protein levels may assist in determining the pathological subtype of appendicitis in pediatric patients.