The oral cavity as a reservoir for resistance- and hypervirulence-associated genes of Klebsiella pneumoniae in hospitalized patients
This study provides the first evidence in Algeria of OXA-48- and NDM-5-producing <i>K. pneumoniae</i> in the oral cavity of hospitalized patients. The coexistence of carbapenem resistance and hypervirulence underscores the oral cavity as a critical reservoir, potentially fueling nosocomial infections and the dissemination of high-risk clones within hospitals and the wider community.
Authors
- Christian Brandt (ORCID: https://orcid.org/0000-0002-7199-3957)
- Celia Diezel
- Stefan Monecke (ORCID: https://orcid.org/0000-0003-4368-8709)
- D. Belhadi
- Amira A. Moawad (ORCID: https://orcid.org/0000-0002-5105-4637)
- Fatma Zohra Zaidi
- Abdelaziz Touati (ORCID: https://orcid.org/0000-0002-7479-2456)
- Mohamed Belmahdi
- Ralf Ehricht (ORCID: https://orcid.org/0000-0002-6612-0043)
- Karima Zenati
- Sascha D. Braun
- E. Müller
- Raouya Mostefaoui
Institutions
- Friedrich-Loeffler-Institut (DE)
- University of Béjaïa (DZ)
- Schiller International University (FR)
- Leibniz Institute of Photonic Technology (DE)
- Ziane Achour University of Djelfa (DZ)
- InfectoGnostics Research Campus Jena (DE)
- Animal Health Research Institute (TW)
- Institute of Virology of the Slovak Academy of Sciences (SK)
- Friedrich Schiller University Jena (DE)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2026-02-05
- DOI
- https://doi.org/10.3389/fmicb.2026.1751947
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 0.00