<i>CLIPPER</i> Regulates LPIN1-Mediated Mitochondrial Biogenesis and Heart Regeneration
Our data identify <i>CLIPPER</i> as a promising therapeutic target for heart regeneration, acting through control of LPIN1-dependent mitochondrial biogenesis and cardiomyocyte proliferation.
Authors
- Daniel Maric
- Isabelle Plaisance
- Francesco Ruberto (ORCID: https://orcid.org/0000-0003-4516-8686)
- Thierry Pedrazzini (ORCID: https://orcid.org/0000-0002-7969-8725)
- Thong Beng Lu
- Luca Braga (ORCID: https://orcid.org/0000-0002-9827-6755)
- Mohamed Nemir (ORCID: https://orcid.org/0009-0009-0632-7235)
- Hashim Ali (ORCID: https://orcid.org/0000-0002-5056-845X)
- Parisa Aghagolzadeh (ORCID: https://orcid.org/0000-0002-1519-5790)
- Tatjana Kleele
- Alexandre Sarre
- Roger S-Y Foo
- Mauro Giacca
- Chang Jie Mick Lee
- Suliana Manley
Institutions
- King's College London (GB)
- ETH Zurich (CH)
- Polyclinic Medical University (CH)
- École Polytechnique Fédérale de Lausanne (CH)
- International Centre for Genetic Engineering and Biotechnology (IT)
- University of Lausanne (CH)
Publication Details
- Journal
- Circulation Research
- Published
- 2026-02-05
- DOI
- https://doi.org/10.1161/circresaha.125.326739
- Citations
- 1
- Primary Topic
- Congenital heart defects research
- Type
- article
- Field-Weighted Citation Impact
- 22.24