The Impact of Immunotherapy on Incidence of Second Primary Malignancies: A Surrogate for Antitumor Surveillance Activation
Treatment of primary cancer with IT was associated with a reduced clinical incidence of SPCs. These findings support further investigation into the potential of IT as a cancer prevention strategy in both cancer survivors and high-risk, cancer-free individuals.
Authors
- Tyler Alban (ORCID: https://orcid.org/0000-0002-3261-140X)
- Ying Ni
- Jacqulyn Tomer
- Preeyal Patel
- Emily Craig Zabor (ORCID: https://orcid.org/0000-0002-1402-4498)
- Monica Lee (ORCID: https://orcid.org/0000-0002-0082-5753)
- Osama Abu-Shawer
- Hadil Zureigat (ORCID: https://orcid.org/0000-0002-9593-2550)
- Bridget Adcock
- Heya Batah
- Austin Ingraham
- Tim Chan
- Alex A. Adjei (ORCID: https://orcid.org/0000-0002-8039-6556)
- Wen Wee Ma
- Moaath K. Mustafa Ali
- Meera Patel
- Aastha Dhakal
- Vladimir Makarov
- Ahmed Hassan
- Scott Robertson
Institutions
- Cleveland Clinic (US)
- Center for Neuroscience and Regenerative Medicine (US)
- Case Comprehensive Cancer Center
Publication Details
- Journal
- Clinical Cancer Research
- Published
- 2026-02-05
- DOI
- https://doi.org/10.1158/1078-0432.ccr-25-3886
- Primary Topic
- Multiple and Secondary Primary Cancers
- Type
- article
- Field-Weighted Citation Impact
- 0.00