Association of Physical Frailty With Serum Growth Differentiation Factor‐15 and Cognitive Decline: A Cross‐Sectional Study
This study suggests a potential involvement of physical frailty in the relationship between serum GDF-15 levels and cognitive decline. Serum GDF-15 levels may have potential as a clinical indicator for frailty-related cognitive decline in the future. Further longitudinal studies are needed to explore this relationship and clarify the role of GDF-15.
Authors
- Noriko Hori (ORCID: https://orcid.org/0000-0002-5497-7250)
- Yosuke Osuka (ORCID: https://orcid.org/0000-0002-5744-1961)
- Yasumoto Matsui (ORCID: https://orcid.org/0000-0001-7105-0919)
- Tohru Hosoyama (ORCID: https://orcid.org/0000-0002-1825-6923)
- Marie Takemura
- Daichi Shigemizu (ORCID: https://orcid.org/0000-0002-4412-0552)
- Kaori Kinoshita (ORCID: https://orcid.org/0000-0003-0141-9076)
- Jiaqi Li (ORCID: https://orcid.org/0000-0002-8308-9850)
- Shosuke Satake
- Kazuhiro Yoshiura
- Georg von Fingerhut
Institutions
- Hiroshima University (JP)
- National Center for Geriatrics and Gerontology (JP)
- Kindai University (JP)
Publication Details
- Journal
- Geriatrics and gerontology international/Geriatrics & gerontology international
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1111/ggi.70377
- Primary Topic
- GDF15 and Related Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 0.00