NLRP12 Alleviated Periodontal Destruction via Suppressing Nuclear Factor Kappa-B Signalling Pathway
NLRP12 suppressed inflammatory responses while enhancing osteogenic differentiation of PDLSCs via downregulating the activation of the nuclear factor kappa-B pathway, indicating that NLRP12 is a latent target for enhancing PDLSCs-based periodontal tissue regeneration.
Authors
- Wenting Zhang (ORCID: https://orcid.org/0009-0004-8931-6171)
- Weiping Wang
- Juefei Wu
- Shuangshuang Xu
- Yuhui Sun
- Gang Ding
Institutions
- Weifang Medical University (CN)
Publication Details
- Journal
- International Dental Journal
- Published
- 2026-02-05
- DOI
- https://doi.org/10.1016/j.identj.2026.109417
- Primary Topic
- Oral microbiology and periodontitis research
- Type
- article
- Field-Weighted Citation Impact
- 0.00