Reduction in overtreatment of gonorrhoea and chlamydia through point-of-care testing compared with syndromic management for vaginal discharge: a modelling study for Zimbabwe

Improved data on the functioning of syndromic management in practice would help refine the estimates of the health impact and the overall value proposition of a highly sensitive POC diagnostic for NG/CT/TV. However, even without such data, our analysis demonstrates the potential for such a diagnostic to reduce overtreatment by >90% relative to plausible assumptions regarding the standard of care.

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Publication Details

Journal
Sexually Transmitted Infections
Published
2026-02-05
DOI
https://doi.org/10.1136/sextrans-2025-056646
Primary Topic
Reproductive tract infections research
Type
article
Field-Weighted Citation Impact
0.00
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article

Reduction in overtreatment of gonorrhoea and chlamydia through point-of-care testing compared with syndromic management for vaginal discharge: a modelling study for Zimbabwe

Cliff C. Kerr, Lori M. Newman, Griffins Manguro, Chido Dziva Chikwari et al.
Sexually Transmitted Infections
Reproductive tract infections research
article

Reduction in overtreatment of gonorrhoea and chlamydia through point-of-care testing compared with syndromic management for vaginal discharge: a modelling study for Zimbabwe

Cliff C. Kerr, Lori M. Newman, Griffins Manguro, Chido Dziva Chikwari, M. Marks, Lauren Snyder, Remco P H Peters, Daniel Klein, Darcy W Rao, Robyn M Stuart
article en

Abstract

Improved data on the functioning of syndromic management in practice would help refine the estimates of the health impact and the overall value proposition of a highly sensitive POC diagnostic for NG/CT/TV. However, even without such data, our analysis demonstrates the potential for such a diagnostic to reduce overtreatment by >90% relative to plausible assumptions regarding the standard of care.

Sexually Transmitted Infections
Gates Foundation (US), Royal London Hospital (GB), London School of Hygiene & Tropical Medicine (GB), Hospital for Tropical Diseases (GB), Biomedical Research and Training Institute (ZW), World Health Organization (CH), University College London (GB)
Gender equality
Openalex Percentile: Top 63%
Reproductive tract infections research
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Reduction in overtreatment of gonorrhoea and chlamydia through point-of-care testing compared with syndromic management for vaginal discharge: a modelling study for Zimbabwe — Cliff C. Kerr, Lori M. Newman, et al. · Sexually Transmitted Infections (2026) | TGRS Research Map | TGRS