NGS identifies novel HLA-DQA1 and DPB1 associations with aplastic anemia in the Kazakhstani population
Class II alleles, including those within <i>DQA1</i> and <i>DPB1</i>, are important genetic factors influencing AA susceptibility in Kazakhstan. It highlights the need for region-specific genetic profiling to improve disease risk assessment and guide therapeutic strategies.
Authors
- Perizat Kanabekova (ORCID: https://orcid.org/0000-0001-5753-4271)
- Wassim Youssef Almawi (ORCID: https://orcid.org/0000-0003-1633-9757)
- Aida Turganbekova (ORCID: https://orcid.org/0000-0002-1514-5910)
- Zhazira Saduakas
- Zhaksylyk Masalimov (ORCID: https://orcid.org/0000-0003-3033-3888)
- D. K. Baimukasheva
- Zhulduz Zhanzakova
- Didara Khamitova
- S. Abdrakhmanova
Institutions
- L. N. Gumilyov Eurasian National University (KZ)
- Russian Research Institute of Hematology and Transfusiology (RU)
- Nazarbayev University (KZ)
- Tunis El Manar University (TN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2026-02-05
- DOI
- https://doi.org/10.3389/fimmu.2026.1752687
- Primary Topic
- Hematopoietic Stem Cell Transplantation
- Type
- article
- Field-Weighted Citation Impact
- 0.00