A regulatory role of novel long non-coding RNA, BAZ1A-AS1, in vascular smooth muscle cell functions during neointima formation in human saphenous veins
We identified a human-specific lncRNA, <i>BAZ1A-AS1</i> , and its predicted cis-regulatory gene, <i>BAZ1A</i> , as key molecular regulators of neointima formation in human SV. These findings highlight the <i>BAZ1A-AS1/BAZ1A</i> axis as a potential therapeutic target for preventing SV graft failure following CABG.
Authors
- Praneet Veerapaneni (ORCID: https://orcid.org/0009-0000-8593-7166)
- Brandee Goo (ORCID: https://orcid.org/0000-0002-9994-6706)
- Ronnie Chouhaita
- David Kim (ORCID: https://orcid.org/0000-0001-6896-6950)
- Neal L. Weintraub
Institutions
- Memorial Sloan Kettering Cancer Center (US)
- Augusta University (US)
- Temple University (US)
Publication Details
- Journal
- bioRxiv (Cold Spring Harbor Laboratory)
- Published
- 2026-02-05
- DOI
- https://doi.org/10.64898/2026.02.03.703576
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- American Heart Association
- National Institutes of Health