Changes in apolipoproteins following ingestion of a beverage delivering β-hydroxybutyrate: results from a randomized placebo-controlled trial

Exogenously induced acute ketosis resulted in a significantly elevated apo C-II compared with the placebo. Further, the levels of apo B were significantly lowered following ingestion of the KEβHB beverage only among individuals with hypertriglyceridemia. Acute nutritional ketosis may be considered as a potential approach to reduce atherogenic triglyceride-rich lipoproteins in individuals at high cardiovascular disease risk.

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Publication Details

Journal
Frontiers in Nutrition
Published
2026-02-05
DOI
https://doi.org/10.3389/fnut.2025.1726174
Primary Topic
Diet and metabolism studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Changes in apolipoproteins following ingestion of a beverage delivering β-hydroxybutyrate: results from a randomized placebo-controlled trial

Maxim S. Petrov, Sakina H. Bharmal, Yutong Liu, Wandia Kimita
Frontiers in Nutrition
Diet and metabolism studies
article

Changes in apolipoproteins following ingestion of a beverage delivering β-hydroxybutyrate: results from a randomized placebo-controlled trial

Maxim S. Petrov, Sakina H. Bharmal, Yutong Liu, Wandia Kimita
article en

Abstract

Exogenously induced acute ketosis resulted in a significantly elevated apo C-II compared with the placebo. Further, the levels of apo B were significantly lowered following ingestion of the KEβHB beverage only among individuals with hypertriglyceridemia. Acute nutritional ketosis may be considered as a potential approach to reduce atherogenic triglyceride-rich lipoproteins in individuals at high cardiovascular disease risk.

Frontiers in NutritionVol. 12
University of Auckland (NZ)
Zero hunger
Openalex Percentile: Top 63%
Diet and metabolism studies
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