Reducing Neuroinflammation via Inhibition of Fibrinogen Deposition and Microglial Activation as an Underlying Mechanism of Paning I Decoction in Ameliorating Parkinson's Disease Symptoms
PNID may serve as a promising complementary therapy for PD. Benefits may come from the repair of the BBB, reduction of fibrinogen deposition, and decline in neuroinflammation by modulating microglial polarization.
Authors
- Jing‐Wen Chen (ORCID: https://orcid.org/0000-0003-0814-8694)
- Yu‐ling Wan
- Rui‐Zhen Wang
- Fang Liu
- Sheng‐Qiang Zhou
- Ming‐Rong Xie
- Jie Zeng
- Bing‐Wu Zhong
- Yan‐Jun Chen
Institutions
- Nanjing University of Chinese Medicine (CN)
- Central South University (CN)
- Hunan University of Traditional Chinese Medicine (CN)
- Second Xiangya Hospital of Central South University (CN)
Publication Details
- Journal
- Immunity Inflammation and Disease
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1002/iid3.70310
- Primary Topic
- Parkinson's Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00