Concordant and Discordant Transcriptomic Signatures of Twin Placentas in the Setting of Preeclampsia
These findings highlight the complexity of preeclampsia pathology in twins. In DT pregnancies complicated by preeclampsia, placental involvement may be asymmetrical, suggesting that disease may arise from a single affected placenta; however, these results require replication.
Authors
- Thomas L. Brown (ORCID: https://orcid.org/0009-0006-6042-2004)
- William E. Ackerman (ORCID: https://orcid.org/0000-0001-7366-3903)
- Irina A. Buhimschi (ORCID: https://orcid.org/0000-0002-1701-1326)
- Guomao Zhao (ORCID: https://orcid.org/0000-0003-4120-8644)
- Hongwu Jing
- Catalin S. Buhimschi
Institutions
- Illinois College (US)
- Wright State University (US)
- University of Illinois Chicago (US)
Publication Details
- Journal
- Hypertension
- Published
- 2026-02-05
- DOI
- https://doi.org/10.1161/hypertensionaha.125.25854
- Primary Topic
- Pregnancy and preeclampsia studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Ohio State University
- Society For Maternal-Fetal Medicine
- University of Illinois at Urbana-Champaign
- University of Illinois at Chicago
- Office of Advanced Cyberinfrastructure