The impact of food addiction on the treatment of eating disorders and obesity: A systematic review

Food addiction (FA) is a complex clinical condition that refers to addiction to highly palatable foods, represented by compulsive eating behavior and an incapacity to control food consumption, similar to other forms of addiction. This review examines the literature on FA and its impact on eating disorders and obesity. Using databases, such as PubMed, Cochrane Library and Google Scholar, recent studies were analyzed to show how FA may reduce treatment effectiveness, increase symptom severity, promote resistance to nutritional or pharmacological interventions, and elevate the risk of relapse. The search strategy used the keywords 'food addiction', 'obesity', 'eating disorders', 'psychotherapy', and 'dietary therapy', limiting the reference period to studies published in the last five years. In reviewing the available articles, several nuances emerged that are fundamental to understanding FA, including neurobiological mechanisms, psychiatric comorbidities, environmental determinants, alterations in the gut microbiota, and the pervasive influence of ultra-processed foods. Taken together, the data indicate that FA not only intensifies symptom manifestation but also contributes to worse outcomes, with reduced compliance to standard treatments and an increased likelihood of relapse. These observations underscore the importance of recognizing FA as a critical component in clinical practice; neglecting its role and symptoms may compromise therapeutic efficacy. Further research is needed to establish integrative treatment models that include FA as a fundamental component of clinical patient care.

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Publication Details

Journal
Physiology & Behavior
Published
2026-02-05
DOI
https://doi.org/10.1016/j.physbeh.2026.115248
Primary Topic
Eating Disorders and Behaviors
Type
article
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article

The impact of food addiction on the treatment of eating disorders and obesity: A systematic review

Giulia Frank, Michela Cirillo, Laura Di Renzo, Anna Laura Amato et al.
Physiology & Behavior
Eating Disorders and Behaviors
article

The impact of food addiction on the treatment of eating disorders and obesity: A systematic review

Giulia Frank, Michela Cirillo, Laura Di Renzo, Anna Laura Amato, Paola Gualtieri, Giada La Placa
article en

Abstract

Food addiction (FA) is a complex clinical condition that refers to addiction to highly palatable foods, represented by compulsive eating behavior and an incapacity to control food consumption, similar to other forms of addiction. This review examines the literature on FA and its impact on eating disorders and obesity. Using databases, such as PubMed, Cochrane Library and Google Scholar, recent studies were analyzed to show how FA may reduce treatment effectiveness, increase symptom severity, promote resistance to nutritional or pharmacological interventions, and elevate the risk of relapse. The search strategy used the keywords 'food addiction', 'obesity', 'eating disorders', 'psychotherapy', and 'dietary therapy', limiting the reference period to studies published in the last five years. In reviewing the available articles, several nuances emerged that are fundamental to understanding FA, including neurobiological mechanisms, psychiatric comorbidities, environmental determinants, alterations in the gut microbiota, and the pervasive influence of ultra-processed foods. Taken together, the data indicate that FA not only intensifies symptom manifestation but also contributes to worse outcomes, with reduced compliance to standard treatments and an increased likelihood of relapse. These observations underscore the importance of recognizing FA as a critical component in clinical practice; neglecting its role and symptoms may compromise therapeutic efficacy. Further research is needed to establish integrative treatment models that include FA as a fundamental component of clinical patient care.

Physiology & BehaviorVol. 308
University of Rome Tor Vergata (IT), Agostino Gemelli University Polyclinic (IT)
Zero hunger
Openalex Percentile: Top 67%
Eating Disorders and Behaviors
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