In Silico Transcriptomic Analysis for Identification of Potential Diagnostic and Prognostic Biomarkers and Therapeutic Targets in Cervical Cancer using a Hybrid Genetic Algorithm–Support Vector Machine Approach

The identified gene signatures may serve as candidates for hypothesis generation and provide a computational framework to prioritize biomarkers and therapeutic targets in cervical cancer. However, these findings are based on <i>in silico</i> analyses and require experimental and clinical validation before translation into practice.

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Publication Details

Journal
Archives of Iranian Medicine
Published
2025-12-01
DOI
https://doi.org/10.34172/aim.34814
Primary Topic
Ferroptosis and cancer prognosis
Type
article
Field-Weighted Citation Impact
0.00

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article

In Silico Transcriptomic Analysis for Identification of Potential Diagnostic and Prognostic Biomarkers and Therapeutic Targets in Cervical Cancer using a Hybrid Genetic Algorithm–Support Vector Machine Approach

Leili Tapak, Mahlagha Afrasiabi, Leila Nezamabadi Farahani
Archives of Iranian Medicine
Ferroptosis and cancer prognosis
article

In Silico Transcriptomic Analysis for Identification of Potential Diagnostic and Prognostic Biomarkers and Therapeutic Targets in Cervical Cancer using a Hybrid Genetic Algorithm–Support Vector Machine Approach

Leili Tapak, Mahlagha Afrasiabi, Leila Nezamabadi Farahani
article en

Abstract

The identified gene signatures may serve as candidates for hypothesis generation and provide a computational framework to prioritize biomarkers and therapeutic targets in cervical cancer. However, these findings are based on <i>in silico</i> analyses and require experimental and clinical validation before translation into practice.

Archives of Iranian MedicineVol. 28(12)
Hamedan University of Medical Sciences (IR), Tarbiat Modares University (IR), Hamedan University of Technology (IR)
Tarbiat Modares University
Good health and well-being
Openalex Percentile: Top 24%
Ferroptosis and cancer prognosis
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