Identification and functional characterization of 11 novel <i>CYP2C19</i> variants in the Chinese Han population

This study reveals a high prevalence of functionally impaired rare <i>CYP2C19</i> variants in the Chinese Han population, underscoring their potential clinical relevance for personalized medicine.

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Publication Details

Journal
Pharmacogenomics
Published
2025-12-12
DOI
https://doi.org/10.1080/14622416.2026.2624546
Primary Topic
Pharmacogenetics and Drug Metabolism
Type
article
Field-Weighted Citation Impact
0.00
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article

Identification and functional characterization of 11 novel CYP2C19 variants in the Chinese Han population

Qi Lin, Pengfei Jin, Zebei Lu, Da-Peng Dai et al.
Pharmacogenomics
Pharmacogenetics and Drug Metabolism
article

Identification and functional characterization of 11 novel CYP2C19 variants in the Chinese Han population

Qi Lin, Pengfei Jin, Zebei Lu, Da-Peng Dai, Peiwu null Geng, Wenfeng Xu, S S Wu, Chunhong Chen, Rucong Liu, Shuanghu Wang, Qiaoling Zhang, Jianping Cai, Yuntong Ma, Aixia Han
article en

Abstract

This study reveals a high prevalence of functionally impaired rare <i>CYP2C19</i> variants in the Chinese Han population, underscoring their potential clinical relevance for personalized medicine.

PharmacogenomicsVol. 26(17-18)
Capital University (US), Capital Medical University (CN), Beijing Hospital (CN), Lishui City People's Hospital (CN)
Openalex Percentile: Top 26%
Pharmacogenetics and Drug Metabolism
DOIOpen Access PDFOpenAlex
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