Association of SARS-CoV-2 infection with long-lasting increase in circulating IL-32 levels

IL-32 levels increased following COVID-19, especially during the initial severe wave, and correlated with some markers of inflammation. IL-32 remained elevated up to one-year post-discharge, suggesting ongoing inflammation and supporting its potential as a biomarker for long-term sequelae.

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Publication Details

Journal
Frontiers in Immunology
Published
2026-02-06
DOI
https://doi.org/10.3389/fimmu.2026.1739258
Primary Topic
Cytokine Signaling Pathways and Interactions
Type
article
Field-Weighted Citation Impact
0.00

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article

Association of SARS-CoV-2 infection with long-lasting increase in circulating IL-32 levels

A. Cherubini, R. Gualtierotti, Chiara Suffritti, Lorenzo Miano et al.
Frontiers in Immunology
Cytokine Signaling Pathways and Interactions
article

Association of SARS-CoV-2 infection with long-lasting increase in circulating IL-32 levels

A. Cherubini, R. Gualtierotti, Chiara Suffritti, Lorenzo Miano, Elena Sinopoli, Daniele Prati, Serena Pelusi, Alessandra Bandera, Giuseppe Enzo Lamorte, Fatima Rahmeh, Luca Vittorio Carlo Valenti, Flora Peyvandi
article en

Abstract

IL-32 levels increased following COVID-19, especially during the initial severe wave, and correlated with some markers of inflammation. IL-32 remained elevated up to one-year post-discharge, suggesting ongoing inflammation and supporting its potential as a biomarker for long-term sequelae.

Frontiers in ImmunologyVol. 17
University of Milan (IT), Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico (IT)
Ministero della Salute
Good health and well-being
Openalex Percentile: Top 64%
Cytokine Signaling Pathways and Interactions
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