Seizure phenotypes and short-term prognosis in neonatal lupus: a multicenter retrospective cohort in China
NLE infants with seizures often exhibit focal seizures and structural brain injury, associated with anti-SSA/Ro positivity, limited maternal HCQ exposure, and hematologic abnormalities. Despite good seizure control, developmental delay was frequent, indicating risk for adverse neurodevelopment.
Authors
- Yuanyuan Peng (ORCID: https://orcid.org/0009-0004-9583-002X)
- Mi Zhou (ORCID: https://orcid.org/0000-0001-6183-738X)
- Xihui Zhou (ORCID: https://orcid.org/0000-0001-8020-3403)
- Haifeng Geng
- Lei Li (ORCID: https://orcid.org/0000-0001-8723-3461)
- Wenqiang Sun (ORCID: https://orcid.org/0000-0002-9281-1737)
- Xinyun Jin
- Jie Huo
- Linzhou Zhu
- Yanliang Yu
- Huawei Wang
- Yue Jiang
- Xue Liu
- Mengzhao Li
- Xueping Zhu
- Jinhui Hu
- Zhirong Xie
- Wenmei Li
- Yihui Li
Institutions
- Xuzhou Medical College (CN)
- Soochow University (TW)
- Yuhuangding Hospital (CN)
- Soochow University (CN)
- Qinzhou Maternity and Child Health Care Hospital (CN)
- Shenzhen Maternity and Child Healthcare Hospital (CN)
- First Affiliated Hospital of Xi'an Jiaotong University (CN)
- Second People’s Hospital of Huai’an (CN)
- Second Affiliated Hospital of Nanjing Medical University (CN)
- Taiwan Centers for Disease Control (TW)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2026-02-05
- DOI
- https://doi.org/10.3389/fimmu.2026.1721089
- Primary Topic
- Systemic Lupus Erythematosus Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00