Tumor suppressor genes, treatments, and survival in US veterans with prostate cancer

TSG alterations were associated with inferior OS in veterans with mHSPC. In this real-world observational study, ARPI-based combination therapy in veterans with TSG alterations was associated with the longest survival.

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Publication Details

Journal
The Oncologist
Published
2026-02-03
DOI
https://doi.org/10.1093/oncolo/oyag033
Primary Topic
Prostate Cancer Treatment and Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Tumor suppressor genes, treatments, and survival in US veterans with prostate cancer

Carley Pickett, E Knoche, Matthew B. Rettig, Ruben Raychaudhuri et al.
The Oncologist
Prostate Cancer Treatment and Research
article

Tumor suppressor genes, treatments, and survival in US veterans with prostate cancer

Carley Pickett, E Knoche, Matthew B. Rettig, Ruben Raychaudhuri, Jason M. Doherty, Daniel B. Eaton, Kara N. Maxwell, R Bruce Montgomery, Joshua Gruber, Martin W Schoen, Krishny Karunanandaa
article en

Abstract

TSG alterations were associated with inferior OS in veterans with mHSPC. In this real-world observational study, ARPI-based combination therapy in veterans with TSG alterations was associated with the longest survival.

The OncologistVol. 31(4)
Cape Town HVTN Immunology Laboratory / Hutchinson Centre Research Institute of South Africa (ZA), University of California, Los Angeles (US), Washington University in St. Louis (US), Fred Hutch Cancer Center (US), VA Puget Sound Health Care System (US), St. Louis VA Medical Center (US), Philadelphia VA Medical Center (US), VA Greater Los Angeles Healthcare System (US), Saint Louis University (US), University of Pennsylvania (US)
Good health and well-being
Openalex Percentile: Top 66%
Prostate Cancer Treatment and Research
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Tumor suppressor genes, treatments, and survival in US veterans with prostate cancer — Carley Pickett, E Knoche, et al. · The Oncologist (2026) | TGRS Research Map | TGRS