Gene and cytokine expression profiles of metastatic colorectal cancer patients post reovirus administration
Reovirus demonstrates potential as an immunomodulatory and cytotoxic adjuvant in <i>KRAS</i>-mutant mCRC by altering key signaling pathways and cytokine profiles. These findings support further investigation into its potential therapeutic contributions.
Authors
- Radhashree Maitra (ORCID: https://orcid.org/0000-0002-5365-5890)
- Vivian Zweig
- Sanjay Goel
Institutions
- Rutgers, The State University of New Jersey (US)
- Yeshiva University (US)
- Washington University in St. Louis (US)
Publication Details
- Journal
- World Journal of Clinical Oncology
- Published
- 2026-02-06
- DOI
- https://doi.org/10.5306/wjco.v17.i2.113428
- Primary Topic
- Virus-based gene therapy research
- Type
- article
- Field-Weighted Citation Impact
- 0.00