GLP-1RA Liraglutide Attenuates Sepsis by Modulating Gut Microbiota and Associated Metabolites

Taken together, our findings indicate that liraglutide mitigates sepsis by modulating the gut microbiota and regulating associated metabolic pathways. Citrulline may represent a potential microbial mediator or exploratory biomarker within this axis, warranting further mechanistic investigation.

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Publication Details

Journal
Nutrients
Published
2026-02-05
DOI
https://doi.org/10.3390/nu18030531
Primary Topic
Gut microbiota and health
Type
article
Field-Weighted Citation Impact
0.00
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article

GLP-1RA Liraglutide Attenuates Sepsis by Modulating Gut Microbiota and Associated Metabolites

Guobing Chen, Fuping Wang, Bing Gong, Jialong Qi et al.
Nutrients
Gut microbiota and health
article

GLP-1RA Liraglutide Attenuates Sepsis by Modulating Gut Microbiota and Associated Metabolites

Guobing Chen, Fuping Wang, Bing Gong, Jialong Qi, Heng Su, Zhuang’e Shi
article en

Abstract

Taken together, our findings indicate that liraglutide mitigates sepsis by modulating the gut microbiota and regulating associated metabolic pathways. Citrulline may represent a potential microbial mediator or exploratory biomarker within this axis, warranting further mechanistic investigation.

NutrientsVol. 18(3)
Kunming University of Science and Technology (CN)
Good health and well-being
Openalex Percentile: Top 65%
Gut microbiota and health
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